Benzonatate and mucinex

Mucinex DM contains dextromethorphan, which is also found in Nyquil. Taking Mucinex DM and Nyquil together could result in too much dextromethorphan in your system, leading to more side effects like dizziness and drowsiness. This combination should be avoided. Mucinex and Dayquil. Mucinex and Dayquil should also be safe to take together.

Having top external computer microphones allows you to communicate more clearly when you are on a call, videoconference, or chatting with your colleagues. If you buy something thro...There is no known drug interaction between azithromycin and Mucinex (guaifenesin). They are considered safe to take together. In fact, Mucinex can be a great medication choice to help clear up the symptoms you are experiencing (chest congestion, excess mucus etc.,). While azithromycin is a commonly used antibiotic for a number of …More about Guaifenesin. Ratings & Reviews. Benzonatate has an average rating of 4.0 out of 10 from a total of 775 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 62% reported a negative effect. Guaifenesin has an average rating of 7.0 out of 10 from a total of 301 ratings on Drugs.com. 64% of reviewers reported a ...Ancient fossilized chlorophyll was dark red and purple, which would have caused ancient water and soil to appear pink. HowStuffWorks looks at this color phenomenon. Advertisement W...The dosage of Mucinex Fast-Max for adults and children over age 12 is 20 milliliters of liquid or two caplets every four hours, according to the Mucinex website. Children under the...

Lozenges, cough drops, and over-the-counter medicines such as dextromethorphan (Robitussin and others) and guaifenesin (Mucinex and others) can help with the cough that often comes with COVID-19. Dextromethorphan could be the choice for the dry cough that COVID-19 is best known for; guaifenesin that for wetter coughs. …The phase IV clinical study analyzes what interactions people who take Benzonatate and Xanax have. It is created by eHealthMe based on reports of 417 people who take Benzonatate and Xanax from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions. With medical big data and AI algorithms ...Apr 11, 2023 · Mucinex is a brand (trade) name for guaifenesin. Mucinex (guaifenesin) acts indirectly on the gastrointestinal vagal nerves which triggers reflex secretion from submucosal glands and goblet cells, increasing the water content of mucus, making it easier for it to be coughed out. Mucinex also affects the secretion of mucus from goblet and Clara ... Interactions between your drugs. No interactions were found between benzonatate and Mucinex Sinus-Max Day & Night (Night). However, this does not necessarily mean no …A total of 393 drugs are known to interact with ibuprofen . Ibuprofen is in the drug class Nonsteroidal anti-inflammatory drugs . Ibuprofen is used to treat the following conditions: Aseptic Necrosis. Back Pain. Chronic Myofascial Pain. Chronic Pain. Costochondritis. Diffuse Idiopathic Skeletal Hyperostosis.Ancient fossilized chlorophyll was dark red and purple, which would have caused ancient water and soil to appear pink. HowStuffWorks looks at this color phenomenon. Advertisement W...

convulsions (seizures) loss of consciousness. no blood pressure or pulse. restlessness. shakiness in the legs, arms, hands, or feet. stopping of the heart. trembling or shaking of the hands or feet. unconsciousness. Some side effects may occur that usually do not need medical attention.Benzonatate (Tessalon Perles) is an antitussive, meaning it's a cough suppressant. It works by numbing certain nerves in your lungs and airways, which …The present study evaluated the effect of benzonatate 200mg (B), guaifenesin 600 mg (G), their combination (B+G), and placebo (P) on capsaicin-induced cough in 30 adult …Drink plenty of water while you are taking guaifenesin; this will help loosen the mucus. It will loosen the mucus in your lungs and encourage expectoration. It won't stop the cough. Tessalon on the other hand works to control the coughing. I do not recommend taking them together without speaking with your doctor first.benzonatate, diphenhydramine, Benadryl, guaifenesin, dextromethorphan, Mucinex, ambroxol, acetylcysteine, dextromethorphan / guaifenesin, Robitussin Cough + Chest Congestion DM Images Mucinex DM Maximum Strength 60 mg / 1200 mg (Mucinex 1200) View all imagesOTC cough medicines, like Mucinex DM, often contain dextromethorphan (a cough suppressant) and guaifenesin (an expectorant). ... Benzonatate (Tessalon): This is a prescription, non-narcotic cough medication that works by numbing the airways and air sacs in the lungs. It is approved for use in adults and children over the age of 10 years.

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With creativity becoming a commodity that so many people trade on, it's more important than ever to have ideas constantly flowing. But are these creative careers only available to ...Mucinex (guaifenesin) and Sudafed (pseudoephedrine) can safely be taken together. In fact, there are a variety of medications that combine both active ingredients. These two meds are used to treat ...Thinner ice in the Arctic sea has been more common and widespread in recent years. On April 14, a group of NASA scientists were flying over the Beaufort Sea, north of Alaska and th...Jul 28, 2022 · Mucinex DM contains dextromethorphan, which is also found in Nyquil. Taking Mucinex DM and Nyquil together could result in too much dextromethorphan in your system, leading to more side effects like dizziness and drowsiness. This combination should be avoided. Mucinex and Dayquil. Mucinex and Dayquil should also be safe to take together.

Mucinex has an average rating of 6.1 out of 10 from a total of 152 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 35% reported a negative effect. Promethazine DM has an average rating of 5.5 out of 10 from a total of 40 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 44% reported a negative …Mucinex DM contains dextromethorphan, which is also found in Nyquil. Taking Mucinex DM and Nyquil together could result in too much dextromethorphan in your system, leading to more side effects like dizziness and drowsiness. This combination should be avoided. Mucinex and Dayquil. Mucinex and Dayquil should also be safe to take together.Descriptions. Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.Benzonatate is used in the treatment of Dry cough. View Benzonatate’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com.“ Benzonatate is a cough medicine that works to reduce the reflex in one’s lungs that creates the urge to cough,” says Po-Chang Hsu, ... (a cough with mucus and phlegm), there are alternatives that can help. For example, Mucinex (guaifenesin) can help a productive cough, while Delsym (dextromethorphan) can help a dry cough.Between 95-99 I was prescribed different things but some I no longer plan on taking here is what I took In the past 24 hours: 650 mg Tylenol sinus (4AM) Mucinex Aleve sinus and cold 200mg Zofran Benzonatate 200mg (yesterday evening and 8-9 this morning) Arbuterol (inhaler) And ipratropium bromide (nasal spray)Common interactions among females include urinary tract infection and wheezing. Common interactions among males include dyspnoea and pain in extremity. The phase IV clinical study analyzes what interactions people have when they take Sudafed and Benzonatate together. It is created by eHealthMe based on data from the FDA, and is updated regularly. Drug interactions are reported among people who take Benzonatate and Mucinex dm. Common interactions among females include erythema and febrile neutropenia. Common interactions among males include bronchial hyperreactivity and chronic kidney disease. The phase IV clinical study analyzes what interactions people have when they take Benzonatate ... Benzonatate is a cough suppressant that relieves cough. It works by calming your cough reflex. Common brand names for this medication include Tessalon®, Perles® and Zonatuss®. Talk to a healthcare provider if your symptoms don’t improve or if they get worse while taking this medication.May 9, 2023 · 2. Mucinex. If the drug interaction potential of dextromethorphan and the adverse effect potential of benzonatate have you looking for other options, Mucinex may meet your needs. Mucinex is one of the brand name forms of guaifenesin, a safe OTC drug that is thought to thin bronchial mucus, making it easier to cough out or expectorate. Answer. Thanks for reaching out to us! Yes, Zyrtec-D (cetirizine; pseudoephedrine) can safely be taken with Mucinex (guaifenesin). There is no drug interaction between them. All three of the drugs that are contained in these two products are in different drug classes and work in different ways to treat cough/cold symptoms.Comparing Benzonatate vs Coricidin HBP Chest Congestion & Cough. Benzonatate. Coricidin HBP Chest Congestion & Cough (dextromethorphan / guaifenesin) Prescription only. Benzonatate relieves a dry cough; however, the capsules must be swallowed whole because the risk of a fatal overdosage is increased if the capsules are opened in any way.

Jul 6, 2010 · Inactive 5 Oct 2010. two depressants and a stimulant are you crazy, one minute you;ll be dopy the next minute you;ll be flying like a kite , if your taking tessalon (benzonatate) you will not need robitussin . and you;ll not be needing mucinex either . do not mix these drugs unless you wnat to feel like crap. +0.

Interactions between your drugs. No interactions were found between benzonatate and Mucinex Sinus-Max Day & Night (Night). However, this does not necessarily mean no …The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ...Lozenges, cough drops, and over-the-counter medicines such as dextromethorphan (Robitussin and others) and guaifenesin (Mucinex and others) can help with the cough that often comes with COVID-19. Dextromethorphan could be the choice for the dry cough that COVID-19 is best known for; guaifenesin that for wetter coughs. …Especially when it comes to my family. So i double checked with our pharmacist when we filled it. She confirmed it was "Completely Safe" for diabetics. I hope this answers your question. +0. MI. mistybanks 23 Jan 2016. Thank you very much for the information. We appreciate you taking the time to respond.Answer. Benzonatate (generic for Tessalon), a medication used to relieve cough, is not known to have many clinically significant drug interactions. In fact, the prescribing information for the drug does not list any. In regard to taking benzonatate with Sudafed, a nasal decongestant, they are not known to have any interaction and are …The azithromycin will take care of the infection, the Mucinex will loosen phlegm and help you breathe and the benzonatate is a cough suppressant. A. Schuyler, NP Category: HealthGet ratings and reviews for the top 10 gutter guard companies in Golden Glades, FL. Helping you find the best gutter guard companies for the job. Expert Advice On Improving Your Ho...Benzonatate is a prescription, non-narcotic antitussive medication. It numbs the airways, the air sacs in the lungs, and the lining of the lungs. It’s FDA-approved for adults and children over 10 years old. You can take up to 600 mg daily, divided into three doses or as otherwise recommended by your healthcare provider.Mucinex DM contains dextromethorphan, which is also found in Nyquil. Taking Mucinex DM and Nyquil together could result in too much dextromethorphan in your system, leading to more side effects like dizziness and drowsiness. This combination should be avoided. Mucinex and Dayquil. Mucinex and Dayquil should also be safe to take together.severe dizziness or anxiety, feeling like you might pass out. Common side effects of Mucinex DM may include: dizziness, drowsiness; sleep problems ( insomnia ); diarrhea; or. feeling nervous, restless, anxious, or irritable. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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Medications to be avoided or used with caution in all patients with Parkinson’s disease. typical antipsychotics. They. dopamine receptors. The. typical antipsychotics. Note: If an antipsychotic that blocks dopamine receptors needs to be used, atypical antipsychotics are better choices than typical antipsychotics. Mucinex is a brand (trade) name for guaifenesin. Mucinex (guaifenesin) acts indirectly on the gastrointestinal vagal nerves which triggers reflex secretion from submucosal glands and goblet cells, increasing the water content of mucus, making it easier for it to be coughed out. Mucinex also affects the secretion of mucus from goblet and …A doctor has provided 1 answer. i was prescribed prednisone 10mg. i have a dry cough . can i take benzonatate while on the prednisone?: Yes: Yes you can take the two together. There are no interactions betw.The phase IV clinical study analyzes what interactions people who take Pepcid and Mucinex have. It is created by eHealthMe based on reports of 520 people who take Pepcid and Mucinex from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions. With medical big data and AI algorithms, … Specialities include: Nutrition, Fitness, Wellness, Rehab, Physical Therapy, Occupational Therapy. HI,Thanks for your question.These two drugs don't interact with each other so yes you can take both of them together.Good luck.I hope this helps you.Please ask for any queryplease click accept if i have answered your questionregardsDR Hasan. Jul 6, 2010 · Inactive 5 Oct 2010. two depressants and a stimulant are you crazy, one minute you;ll be dopy the next minute you;ll be flying like a kite , if your taking tessalon (benzonatate) you will not need robitussin . and you;ll not be needing mucinex either . do not mix these drugs unless you wnat to feel like crap. +0. More about Robitussin Chest Congestion ( guaifenesin ) Ratings & Reviews. Mucinex has an average rating of 6.1 out of 10 from a total of 152 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 35% reported a negative effect. Be the first to share your experience with this drug.Mucinex has an average rating of 6.1 out of 10 from a total of 152 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 35% reported a negative effect. Guaifenesin has an average rating of 7.0 out of 10 from a total of 301 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 25% reported a negative …Jul 6, 2010 · Inactive 5 Oct 2010. two depressants and a stimulant are you crazy, one minute you;ll be dopy the next minute you;ll be flying like a kite , if your taking tessalon (benzonatate) you will not need robitussin . and you;ll not be needing mucinex either . do not mix these drugs unless you wnat to feel like crap. +0. Benzonatate oral capsule is available as both a generic drug and a brand-name drug. Brand name: Tessalon. Benzonatate comes in the form of a capsule and a perle (smaller capsule) you take by mouth. Benzonatate is used to relieve coughs due to colds or influenza (flu). It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. ….

Get ratings and reviews for the top 11 gutter guard companies in Olney, MD. Helping you find the best gutter guard companies for the job. Expert Advice On Improving Your Home All P...May 9, 2023 · 2. Mucinex. If the drug interaction potential of dextromethorphan and the adverse effect potential of benzonatate have you looking for other options, Mucinex may meet your needs. Mucinex is one of the brand name forms of guaifenesin, a safe OTC drug that is thought to thin bronchial mucus, making it easier to cough out or expectorate. Benzonatate (Tessalon) is a prescription medication for managing a cough. While it is usually well tolerated, it has a few potential side effects. Common benzonatate side effects include dizziness, drowsiness, and headache. Constipation and nausea can happen, too. Most side effects are generally mild, can be managed at home, and go …Identification Summary. Benzonatate is a non-narcotic oral antitussive drug used to suppress coughing.. Generic Name Benzonatate DrugBank Accession Number DB00868 Background. Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. 3 Currently, benzonatate is the only non …Can or should I mix oseltamiver and benzonatate with mucinex. 4.25.2024. Chris S M.D. Emergency Medicine Physician. 668 Satisfied Customers. I was prescribed benzonatate to aid my cough for covid 19, I. 4.25.2024. Onlinedoc. Doctor. 7,568 Satisfied Customers. I have alittle lung congestion associated with a cold I had. Benzonatate is used to relieve coughs due to colds or influenza (flu). It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. No, Mucinex and benzonatate belong to different drug classes. Mucinex is an expectorant, which thins mucus and makes it easier to cough up. Benzonatate is an antitussive, which suppresses a cough. Mucinex DM is a prescription and over the counter drug used to relieve chest congestion. Mucinex DM is used to control coughs and other mild respiratory conditions including the common cold and allergies. Mucinex DM works by thinning the thick mucus found inside the chest or nose to help persons breathe easily. Benzonatate and mucinex, Jun 1, 2009 · Benzonatate, a long chain polyglycol derivative chemically related to procaine, is a peripherally-acting, oral anesthetic agent whose mechanism of cough suppression is believed to involve inhibition of pulmonary stretch receptors. 10 Studies performed soon after its approval in the United States a half century ago showed benzonatate able to ... , Drugs & Medications. Mucinex - Uses, Side Effects, and More. Generic Name (S): guaifenesin. Uses. This medication is used for the temporary relief of coughs caused by …, What Is Mucinex? Mucinex (guaifenesin) is classified as an expectorant and helps to loosen/thin mucus, making it easier to remove from the airways. Like antihistamines, Mucinex is a common component of many different cough/cold products. Final Words. So again, there is no problem taking both Zyrtec and Mucinex together., Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan. , There is no known drug interaction between azithromycin and Mucinex (guaifenesin). They are considered safe to take together. In fact, Mucinex can be a great medication choice to help clear up the symptoms you are experiencing (chest congestion, excess mucus etc.,). While azithromycin is a commonly used antibiotic for a number of indications ..., The present study evaluated the effect of benzonatate 200mg (B), guaifenesin 600 mg (G), their combination (B+G), and placebo (P) on capsaicin-induced cough in 30 adult nonsmokers with acute URI. On 3 separate days within a 7-day period, 1h after ingesting randomly assigned study drug in a double-blind fashion, subjects underwent capsaicin ..., Summary: Drug interactions are reported among people who take Benzonatate and Mucinex. Common interactions among females include headache and diarrhoea. Common interactions among males include chronic kidney disease and pneumonia. The phase IV clinical study analyzes what interactions people have when they take Benzonatate and …, Useless for any other cough. When you've cleared the virus but your lungs are healing and sensitive to stretch, and taking a deep breath can trigger a coughing jag that makes you nearly puke, but there's no sputum no fever no nasal congestion - try tessalon. It works by anesthetizing stretch receptors in the lungs. Reply reply., Mucinex DM contains dextromethorphan, which is also found in Nyquil. Taking Mucinex DM and Nyquil together could result in too much dextromethorphan in your system, leading to more side effects like dizziness and drowsiness. This combination should be avoided. Mucinex and Dayquil. Mucinex and Dayquil should also be safe to take together., Benzonatate is used in the treatment of Dry cough. View Benzonatate’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com., Descriptions. Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough., Dosage for Benzonatate. Adults and Children over 10 years of age: Usual dose is one 100 mg or 200 mg capsule three times a day as needed for cough. If necessary to control cough, up to 600 mg daily in three divided doses may be given. Benzonatate should be swallowed whole., Summary: Drug interactions are reported among people who take Benzonatate and Mucinex. Common interactions among females include headache and diarrhoea. Common interactions among males include chronic kidney disease and pneumonia. The phase IV clinical study analyzes what interactions people have when they take Benzonatate and Mucinex together. , Between 95-99 I was prescribed different things but some I no longer plan on taking here is what I took In the past 24 hours: 650 mg Tylenol sinus (4AM) Mucinex Aleve sinus and cold 200mg Zofran Benzonatate 200mg (yesterday evening and 8-9 this morning) Arbuterol (inhaler) And ipratropium bromide (nasal spray), Some of us are so used to using multiple monitors, it would be near impossible to give them up. Others are happy with just one display. Do you think multiple monitors make you more..., Some dosage forms listed on this page may not apply to the brand name Mucinex. Applies to guaifenesin: oral liquid, oral solution, oral syrup, oral tablet, oral tablet extended release. Serious side effects of Mucinex. Along with its needed effects, guaifenesin (the active ingredient contained in Mucinex) may cause some unwanted …, Benzonatate has an average rating of 4.0 out of 10 from a total of 776 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 62% reported a negative effect. Mucinex has an average rating of 6.1 out of 10 from a total of 152 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 35% reported a negative …, Aug 14, 2023 · Some of these side effects may result from chewing or sucking on a benzonatate capsule. Common benzonatate side effects may include: headache, dizziness; nausea, upset stomach; constipation; itching, rash; or. stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. , benzonatate, diphenhydramine, Benadryl, guaifenesin, dextromethorphan, Mucinex, ambroxol, acetylcysteine, dextromethorphan / guaifenesin, Robitussin Cough + Chest Congestion DM Images Mucinex DM Maximum Strength 60 mg / 1200 mg (Mucinex 1200) View all images, Inactive 5 Oct 2010. two depressants and a stimulant are you crazy, one minute you;ll be dopy the next minute you;ll be flying like a kite , if your taking tessalon (benzonatate) you will not need robitussin . and you;ll not be needing mucinex either . do not mix these drugs unless you wnat to feel like crap. +0., “ Benzonatate is a cough medicine that works to reduce the reflex in one’s lungs that creates the urge to cough,” says Po-Chang Hsu, ... (a cough with mucus and phlegm), there are alternatives that can help. For example, Mucinex (guaifenesin) can help a productive cough, while Delsym (dextromethorphan) can help a dry cough., Azithromycin (Oral Route) Azithromycin is used to treat certain bacterial infections in many different parts of the body. Azithromycin is used to prevent and treat a very serious type of infection (mycobacteria or MAC). It is a macrolide-type antibiotic. It works by stopping the growth of bacteria., The present study evaluated the effect of benzonatate 200mg (B), guaifenesin 600 mg (G), their combination (B+G), and placebo (P) on capsaicin-induced cough in 30 adult nonsmokers with acute URI. On 3 separate days within a 7-day period, 1h after ingesting randomly assigned study drug in a double-blind fashion, subjects underwent capsaicin ..., Apr 17, 2019 · Does Benzonatate make you loopy like a narcotic cough medication or just sleepy like Benadryl? I've seen several reviews of people saying it made them really sleepy & one person used the word "loopy". I've finished a Z pack but still have a cough that keeps me up @ night, makes my chest, ribs, & back hurt, & even gets going so much that I gag. , What Is Mucinex? Mucinex (guaifenesin) is classified as an expectorant and helps to loosen/thin mucus, making it easier to remove from the airways. Like antihistamines, Mucinex is a common component of many different cough/cold products. Final Words. So again, there is no problem taking both Zyrtec and Mucinex together., Benzonatate is used in the treatment of Dry cough. View Benzonatate’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com., Answer. Thanks for reaching out to us! Yes, Zyrtec-D (cetirizine; pseudoephedrine) can safely be taken with Mucinex (guaifenesin). There is no drug interaction between them. All three of the drugs that are contained in these two products are in different drug classes and work in different ways to treat cough/cold symptoms., Comparing Benzonatate vs Coricidin HBP Chest Congestion & Cough. Benzonatate. Coricidin HBP Chest Congestion & Cough (dextromethorphan / guaifenesin) Prescription only. Benzonatate relieves a dry cough; however, the capsules must be swallowed whole because the risk of a fatal overdosage is increased if the capsules are opened in any way. , Benzonatate and Mucinex (guaifenesin) are two different medicines used to treat cough. Mucinex is an expectorant that helps to loosen mucus and relieve …, , Medications to be avoided or used with caution in all patients with Parkinson’s disease. typical antipsychotics. They. dopamine receptors. The. typical antipsychotics. Note: If an antipsychotic that blocks dopamine receptors needs to be used, atypical antipsychotics are better choices than typical antipsychotics. , The phase IV clinical study analyzes what interactions people who take Pepcid and Mucinex have. It is created by eHealthMe based on reports of 520 people who take Pepcid and Mucinex from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions. With medical big data and AI algorithms, …, Comparing Benzonatate vs Coricidin HBP Chest Congestion & Cough. Benzonatate. Coricidin HBP Chest Congestion & Cough (dextromethorphan / guaifenesin) Prescription only. Benzonatate relieves a dry cough; however, the capsules must be swallowed whole because the risk of a fatal overdosage is increased if the capsules are opened in any way.